87 Streptococci-, 161 S. aureus- and 100 Enterobacteriaceae strains we
re isolated from bovine mastitis cases. They were tested regarding in-
vitro sensitivity against 11 different antibiotics. Minimal inhibitory
concentrations were determined by means of Sensititre(R)-microplate m
ethod, by which evidence is given concerning essential tissue concentr
ations. Streptococci displayed very different resistance pattern again
st antibiotics, Enterococci an evident higher resistance against penic
illin. More than 80 % of S. aureus strains tested were highly sensitiv
e to beta-lactamantibiotics and aminoglycosides as well. Our examinati
ons have shown that aminoglycosides as well as cephalosporines are rec
ommended for therapeutic use in case of mastitis caused by gram-negati
ve pathogens.