As the leading cause of physician office visits and loss of time from
school as well as the cause of significant morbidity among young child
ren, respiratory infections impose a major burden on the health care s
ystem. The most common causative pathogens are Streptococcus pneumonia
e, Haemophilus influenzae and Moraxella catarrhalis. In young children
acute otitis media and sinusitis may present with relatively nonspeci
fic symptoms such as irritability. Older children may complain of more
specific problems; for example those with otitis media may complain o
f otalgia. Upper respiratory tract infections are typically diagnosed
by signs and symptoms and treated empirically with an antimicrobial ag
ent that offers coverage of the usual causative respiratory pathogens.