ESCHERICHIA-COLI O157-H7 REQUIRES INTIMIN FOR ENTEROPATHOGENICITY IN CALVES

Authors
DEANNYSTROM EA BOSWORTH BT MOON HW OBRIEN AD
Citation
Ea. Deannystrom et al., ESCHERICHIA-COLI O157-H7 REQUIRES INTIMIN FOR ENTEROPATHOGENICITY IN CALVES, Infection and immunity, 66(9), 1998, pp. 4560-4563
Citations number
22
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
66
Issue
9
Year of publication
1998
Pages
4560 - 4563
Database
ISI
SICI code
0019-9567(1998)66:9<4560:EORIFE>2.0.ZU;2-D
Abstract
Enterohemorrhagic Escherichia coli (EHEC) strains require intimin to i nduce attaching and effacing (A/E) lesions ire newborn piglets. Infect ion of newborn calves with intimim-positive or intimin-negative EHEC O 157: H7 demonstrated that intimin is weeded for colonization, A/E lesi ons, and disease in cattle. These results suggest that experiments to determine if intimin-based vaccines reduce O157:H7 levels in cattle ar e warranted.