T. Wendt et al., FULL WORKING CAPACITY OR THREATENED RETIREMENT - THROMBENDARTERECTOMYIN A CASE OF CHRONIC THROMBOEMBOLIC PULMONARY-HYPERTENSION, Deutsche Medizinische Wochenschrift, 123(33), 1998, pp. 965-971
History and clinical findings: A 56-year-old man in marked right heart
failure (stage III-IV of the New York Heart Association classificatio
n) and severe pulmonary hypertension was admitted to a rehabilitation
clinic for therapeutic and social-medical assessment. On physical exam
ination the important features were markedly distended neck veins, tac
hycardia at rest (90/min), a loud 2(nd) pulmonary sound and dyspnea. I
nvestigations and diagnosis: Non-invasive tests (ECC, echocardiography
, abdominal ultrasound and lung functions) confirmed right heart failu
re; invasively obtained haemodynamic data indicated its severity. Sele
ctive pulmonary angiography defined the embolisation to be central and
bilateral. Treatment and course: As intensive drug treatment and phys
iotherapy had failed to achieve significant improvement, operative rem
oval of the bilateral central and some segmental pulmonary thrombi was
performed and an inferior vena caval filtre inserted. Immediately aft
er operation the markedly elevated right-heart and pulmonary artery pr
essures fell markedly and there was dramatic improvement in the patien
t's general condition and in his physical capacity. Angiography demons
trated largely normal pulmonary perfusion. Instead of the anticipated
retirement, the patient was discharged on anticoagulants, in the expec
tation of a return to full-time work. Conclusion: With pulmonary throm
bendarterectomy severe chronic thromboembolic pulmonary hypertension m
ay well be treated.