FATAL PARAPHENYLENEDIAMINE (HAIR DYE) INTOXICATION IN A CHILD RESEMBLING LUDWIGS ANGINA

Citation
M. Lifshits et al., FATAL PARAPHENYLENEDIAMINE (HAIR DYE) INTOXICATION IN A CHILD RESEMBLING LUDWIGS ANGINA, Journal of toxicology. Clinical toxicology, 31(4), 1993, pp. 653-656
Citations number
7
Categorie Soggetti
Toxicology
ISSN journal
07313810
Volume
31
Issue
4
Year of publication
1993
Pages
653 - 656
Database
ISI
SICI code
0731-3810(1993)31:4<653:FP(DII>2.0.ZU;2-U
Abstract
A 6 year-old child with paraphenylenediamine intoxication is presented . The patient suffered from sore throat, cough, and anorexia, followed by severe dyspnea caused by edema of the tongue, pharynx, and neck, r enal failure. and metabolic acidosis. A presumptive diagnosis of Ludwi g's angina, a severe anaerobic infection of the sublingual neck space, was entertained. Despite institution of vigorous supportive therapy a nd administration of antibiotics, the child developed irreversible ven tricular fibrillation and died eight hours after admission. Two days a fter the patient's death, his father recalled that the child and his d og ingested an unidentified substance shortly before the onset of the child's symptoms. The dog died within a few hours. The substance was i dentified as the hair dye, paraphenylenediamine.