YAC STS MAP OF 15 MB OF XP21.3-P11.3, AT 100 KB RESOLUTION, WITH REFINED COMPARISONS OF GENETIC DISTANCES AND DMD STRUCTURE/

Authors
NAGARAJA R JERMAK C TRUSGNICH M YOON J MACMILLAN S MCCAULEY B BROWNSTEIN B SCHLESSINGER D
Citation
R. Nagaraja et al., YAC STS MAP OF 15 MB OF XP21.3-P11.3, AT 100 KB RESOLUTION, WITH REFINED COMPARISONS OF GENETIC DISTANCES AND DMD STRUCTURE/, Gene, 215(2), 1998, pp. 259-267
Citations number
26
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
215
Issue
2
Year of publication
1998
Pages
259 - 267
Database
ISI
SICI code
0378-1119(1998)215:2<259:YSMO1M>2.0.ZU;2-9
Abstract
The 15 Mb region between DXS997 and DXS8054 in Xp21.3-p11.3 has been m apped at seven-fold average coverage in yeast artificial chromosomes ( YACs) and 100 kb inter-sequence tagged site (STS) distance. YACs from six different collections show self-consistent maps. The STSs include 18 (CA) repeat and one tetranucleotide repeat marker that detect polym orphism, as well as eight well-studied genes, a second site for MXS1 s equences, and three expressed sequence tags (ESTs). One of the ESTs ma ps to intron 7 of Duchenne muscular dystrophy, and seems to be a proce ssed intronic sequence with a poly(A) tail. (C) 1998 Elsevier Science B.V. All rights reserved.