PRIMARY HEPATIC OSTEOSARCOMA - CASE-REPORT AND LITERATURE-REVIEW

We describe a primary osteosarcoma of the liver in a 72 year old man. The man was symptomatic and had suffered abdominal pain and distension for four months before he died. At autopsy a large tumor of the liver with direct extension into adjacent structures was found. There was n o evidence of primary tumor or primary bone lesion at any other site. Histologically, the tumor comprised malignant cells producing abundant osteoid arranged in a lace-like pattern. Smaller chondroblastic and f ibroblastic components were also present. These findings were in keepi ng with a diagnosis of primary hepatic osteosarcoma.