SYNTHESIS OF EPOTHILONES - STEREOSELECTIVE ROUTES TO EPOTHILONE-B

Citation
D. Schinzer et al., SYNTHESIS OF EPOTHILONES - STEREOSELECTIVE ROUTES TO EPOTHILONE-B, Synlett, (8), 1998, pp. 861
Citations number
48
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
09365214
Issue
8
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):8<861:SOE-SR>2.0.ZU;2-A
Abstract
In connection with our studies of the total syntheses of epothilones w e report our efforts on the syntheses of epothilone B using a macro-la ctonization and a metathesis approach. Key reaction for the solution o f the acyclic stereoselection is a stereoselective aldol reaction.