POLYMER-BOUND 3,5-CYCLOHEXADIENE-1,2-DIOLS AS CORE STRUCTURES FOR THEDEVELOPMENT OF SMALL-MOLECULE LIBRARIES

Authors
WENDEBORN S DEMESMAEKER A BRILL WKD
Citation
S. Wendeborn et al., POLYMER-BOUND 3,5-CYCLOHEXADIENE-1,2-DIOLS AS CORE STRUCTURES FOR THEDEVELOPMENT OF SMALL-MOLECULE LIBRARIES, Synlett, (8), 1998, pp. 865
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):8<865:P3ACSF>2.0.ZU;2-#
Abstract
A highly efficient sequence for the synthesis of complex, chiral and h ighly functionalized molecules on solid phase is reported. Solid phase bound cyclohexadiene-diols were derivatized through epoxidation, nucl eophilic ring opening, Pd(0) cross-couplings and Diels-Alder reactions .