FROM TOLUENE TO TAXOL(TM) - CHEMOENZYMATIC AND ENANTIODIVERGENT ROUTES TO THE AB-RING SYSTEMS OF TAXOIDS AND ENT-TAXOIDS

Authors
BANWELL MG DARMOS P MCLEOD MD HOCKLESS DCR
Citation
Mg. Banwell et al., FROM TOLUENE TO TAXOL(TM) - CHEMOENZYMATIC AND ENANTIODIVERGENT ROUTES TO THE AB-RING SYSTEMS OF TAXOIDS AND ENT-TAXOIDS, Synlett, (8), 1998, pp. 897
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):8<897:FTTT-C>2.0.ZU;2-#
Abstract
The cis-1,2-dihydrocatechol 2 has been converted, via reaction sequenc es including Diels-Alder cycloaddition and anionic oxy-Cope rearrangem ent steps, into the enantiopure bicyclo[5.3.1]undecanes 20 and 33 whic h correspond to the AB-ring systems of ent-taxoids and taxoids, respec tively.