CU(I)-BINAPHTHYLDIIMINE CATALYZED ASYMMETRIC CYCLOPROPANATION OF OLEFIN WITH DIAZOACETATE

Authors
SUGA H FUDO T IBATA T
Citation
H. Suga et al., CU(I)-BINAPHTHYLDIIMINE CATALYZED ASYMMETRIC CYCLOPROPANATION OF OLEFIN WITH DIAZOACETATE, Synlett, (8), 1998, pp. 933
Citations number
33
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):8<933:CCACOO>2.0.ZU;2-9
Abstract
Chiral l-N,N'-bis(2,6-dichloro-benzy-lidene)-2,2'-diamine (1) was foun d to be an effective ligand for the copper-catalyzed enantioselective cyclopropanation of olefin with l-menthyl diazoacetate. For example, t he reaction of 1,1-diphenylethylene with l-menthyl diazoacetate in the presence of CuOTf-1 complex in CH2Cl2 at - 40 degrees C gave the corr esponding cyclopropanecarboxylate in 98% ee.