GENERATION OF 2-SUBSTITUTED-2-METALLO-1,3-DITHIANES AND THEIR COUPLING WITH 1,2-DISUBSTITUTED EPOXIDES AT ROOM-TEMPERATURE

Authors
IDE M YASUDA M NAKATA M
Citation
M. Ide et al., GENERATION OF 2-SUBSTITUTED-2-METALLO-1,3-DITHIANES AND THEIR COUPLING WITH 1,2-DISUBSTITUTED EPOXIDES AT ROOM-TEMPERATURE, Synlett, (8), 1998, pp. 936
Citations number
48
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
8
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):8<936:GO2ATC>2.0.ZU;2-B
Abstract
2-Substituted-1,3-dithianes were subjected to lithiation by n-BuLi at room temperature and the resulting anions reacted with 1,2-disubstitut ed epoxides at room temperature, giving the coupling products in satis factory yield. In addition, a mixed organometallic reagent, n-BuLi/Bu2 Mg, was found to be an effective metallation reagent for 2-substituted -1,3-dithianes.