Jm. Reimund et al., STERILE OSTEONECROSIS IN 2 PATIENTS WITH INFLAMMATORY BOWEL-DISEASE, Gastroenterologie clinique et biologique, 22(6-7), 1998, pp. 634-638
Aseptic osteonecrosis is a rare extraintestinal manifestation in patie
nts with inflammatory bowel disease; its true prevalence is not precis
ely known. Steroid treatment undoubtedly participates in the pathophys
iology of avascular osteonecrosis, however; other factors like hyperco
agulability may be involved Two cases of bilateral osteonecrosis of th
e knees - the first occurring during the course of ulcerative colitis,
the second lit a patient presenting with Crohn's disease - are descri
bed Specific location of the lesions and regression of symptoms, as we
ll as the importance of magnetic resonance imaging for early recogniti
on of osteonecrosis, are noteworthy.