CRYSTAL-STRUCTURE OF A HYDRATED N-GLYCOPROTEIN LINKAGE REGION MODEL AND ITS ANALOG - HYDROGEN-BONDING AND PI-PI STACKING DRIVEN MOLECULAR ASSEMBLY

Authors
SRIRAM D LAKSHMANAN T LOGANATHAN D SRINIVASAN S
Citation
D. Sriram et al., CRYSTAL-STRUCTURE OF A HYDRATED N-GLYCOPROTEIN LINKAGE REGION MODEL AND ITS ANALOG - HYDROGEN-BONDING AND PI-PI STACKING DRIVEN MOLECULAR ASSEMBLY, Carbohydrate research, 309(3), 1998, pp. 227-236
Citations number
16
Categorie Soggetti
Chemistry Applied","Chemistry Inorganic & Nuclear",Biology
Journal title
Carbohydrate research → ACNP
ISSN journal
00086215
Volume
309
Issue
3
Year of publication
1998
Pages
227 - 236
Database
ISI
SICI code
0008-6215(1998)309:3<227:COAHNL>2.0.ZU;2-J
Abstract
X-Ray diffraction analysis of a hydrated N-glycoprotein linkage region model, -acetamido-2-deoxy-beta-D-glucopyranosyl)acetamide (1) and its N-1-benzamido analogue 2 reveals very interesting molecular architect ure involving seven hydrogen bonds in both compounds and further stabi lization of packing in 2 due to pi-pi stacking. The crystal structure has a two dimensional network of hydrogen bonds formed by infinite cha ins running along the b-axis and homodromic cycles, intersecting at th e water oxygens. (C) 1998 Elsevier Science Ltd. All rights reserved.