B. Brady et R. Darcy, BISTHIOCYCLOMALTO-OLIGOSACCHARIDES WITH TREHALOSYL AND OCTYL LINKS - THEIR SYNTHESIS FOR DUAL-CAVITY INCLUSION, Carbohydrate research, 309(3), 1998, pp. 237-241
6,6'-Dithio-alpha,alpha-trehalose has been prepared, and its thiolate
dianion reacted with 6(I)-O-p-tolyl-sulfonylcyclomaltoheptaose to form
the trehalosyl-linked thiocyclodextrin dimer 5. Another cyclodextrin
dimer (6) having the more flexible octyl link was similarly synthesise
d. Formation of a 1:1 complex with Methyl Orange at pH 4 by dual-cavit
y inclusion was confirmed for 5 and 6. (C) 1998 Elsevier Science Ltd.
All rights reserved.