Some patients with Peutz-Jeghers syndrome may be disturbed by the appe
arance of lentigines. Such patients require management of their lentig
ines as well as their gastro-intestinal polyps. We describe ruby laser
therapy of labial lentigines in two children with Peutz-Jeghers syndr
ome. The response to treatment was excellent and no sequelae or recurr
ence of the lesions was noted.