A distal arteriovenous fistula was created secondarily in an innervate
d radial forearm Free flap, to salvage the neophallus in three female-
to-male transsexuals. This resulted in permanent edema and an arterial
thrill in the neophallus. The arteriovenous fistulas were closed afte
r 6 weeks to 20 months. Acute endothelial damage with risk of thrombos
is, due to ischemia and exposure to arterial blood pressure, may be ex
pected to have been repaired 4 to 6 weeks after arterialization of the
veins. intimal thickening will have started by then, but a subsequent
decrease in vascular luminal diameter may still be expected to be rev
ersible. The authors conclude that ligation of the distal arteriovenou
s fistula may safely be performed some 6 weeks after the salvage proce
dure.