Both galaxy distances and velocities are required for the determinatio
n of the expansion rate of the Universe, as described by the Hubble co
nstant H-0. The radial velocities of galaxies arise not just from this
expansion but also from random components and large-scale flows. To r
each out to distances dominated by the overall cosmic expansion, it is
necessary to probe large physical scales where galaxy-galaxy and gala
xy-cluster interactions become less important. But accurate distances
of nearby galaxies and clusters (commonly measured(1) using Cepheid va
riable stars) are nevertheless required to calibrate the indirect dist
ance indicators generally used to measure these large scales. Here we
report a Cepheid distance of 18.6 +/- 1.9 (statistical error) +/- 1.9
Mpe (systematic error) for the galaxy NGC1365 in Fornax, a cluster of
galaxies in the Southern Hemisphere. We find a value of H-0 = 70 km s(
-1) Mpc(-1) from Fornax alone, and 73 km s(-1) Mpc.(-1) from the inter
vening galaxy flow, each corrected for infall into the Virgo cluster.
These values are consistent with the Hubble constant measured in the f
ar field using secondary methods(2). Our data support previous suggest
ions(3-5) that the local small-scale velocity field has very small sca
tter (similar to+/-70km s(-1)).