Mbh. Smith et al., CHARACTERISTICS OF CHILDREN HOSPITALIZED WITH MILD TO MODERATELY SEVERE ASTHMA, Pediatric asthma, allergy & immunology, 12(2), 1998, pp. 139-146
This retrospectively matched case-control study was conducted to ident
ify historical and clinical characteristics of children admitted for h
igh dependency asthma care (intravenous fluids and steroids, continuou
s oxygen need, and frequent bronchodilator aerosols) and compare them
with those requiring only oral steroids and infrequent bronchodilator
aerosols. The study population consisted of patients with asthma admit
ted to a pediatric hospital (providing primary through tertiary care).
The health records of 112 children admitted (May 1994 to April 1996)
for high dependency care (severe group) were compared with an equal nu
mber of children admitted for standard care (mild group) of asthma and
matched for age and sex (boys: n = 128; girls: n = 96; mean ages: 4.6
5 years and 4.9 years, respectively). Those in the severe group were a
ssociated with a longer median length of stay (LOS)-4.0 days versus 2.
0 days (p < 0.00001). The duration of diagnosed asthma, previous admis
sions, and environmental histories were similar in each group. Regular
home bronchodilator use preceding the admission was associated with a
severe episode (p < 0.001). Prehospital duration of symptoms or treat
ment of the exacerbation did not predict severity. Logistic regression
(controlling for sex and age) indicated regular bronchodilator use or
low oxygen saturation (less than or equal to 90%) prior to treatment
was strongly associated with intensive therapy. Many historical featur
es, such as the duration of diagnosed asthma, previous admissions, and
environmental histories (smokers, presence of animals), do not reliab
ly predict the need for, nor duration of, intensive therapy for asthma
. Some children with mild disease on presentation may become very ill.
However, a history of regular, monthly bronchodilator use is importan
t as a marker for severe disease or inappropriate management. A low ox
ygen saturation at presentation is a useful predictor of the need for
intensive asthma management.