A patient with recurrent retroperitoneal liposarcoma had multiple susp
ected metastases. I-123 BMIPP imaging showed areas of increased uptake
due to accumulation in the myxoid components of the liposarcoma. Ga-6
7 showed accumulation in the undifferentiated components. The well-dif
ferentiated components showed little accumulation of either I-123 BMIP
P or Ga-67. Differences in the accumulation of these radionuclides may
reflect differences in cell densities, fatty acid metabolism, and the
degree of malignancy. I-123 BMIPP and Ga-67 scintigraphy may be usefu
l in determining the prognosis of liposarcoma.