N. Gordon et al., ESTIMATION OF CORONARY BLOOD-FLOW BY ECG GATED CARDIAC THERMOGRAPHY IN OPEN-CHEST CONDITIONS, Physiological measurement, 19(3), 1998, pp. 353-366
Thermography is suggested as a tool to estimate myocardial and coronar
y epicardial how in open-chest heart surgery. To test the feasibility
and compare various methods for coronary flow estimation in open-chest
surgery, thermographic imaging was applied to eight open-chest dogs w
hich were injected with cold saline into the aortic root. Blood flow i
n the left arterial descending (LAD) coronary vessel was measured by a
transit-time flowmeter. ECG gated images were acquired for 20-30 s, w
hile the cold saline (20 mi) was injected into the aortic root. Severa
l flow levels were achieved during repeated hyperaemic response to tra
nsient occlusions of the LAD. A temperature response curve for each fl
ow level was obtained by averaging over an edge-detected arterial segm
ent for each image frame. Several indices were calculated from the tem
perature curve and correlated with the measured coronary flow. These i
nclude: an index based on a corrective heat transfer model (r = 0.69,
p < 0.001), the slope of the descending part of the response curve (I
= 0.76, p < 0.001), the peak temperature difference (r = 0.66, p < 0.0
01), and the area above the temperature response curve (r = 0.61, p <
0.01). As shown, coronary flow can be estimated quantitatively by intr
aoperative epicardial thermography, and may therefore provide importan
t on-line information regarding blood flow during open-chest surgical
procedures. Further studies are required for optimal application of th
is technique so as to increase its potential as a valid clinical tool.