PROPAGATION AND LOCALIZATION OF WNT SIGNALING

Authors
GUMBINER BM
Citation
Bm. Gumbiner, PROPAGATION AND LOCALIZATION OF WNT SIGNALING, Current opinion in genetics & development, 8(4), 1998, pp. 430-435
Citations number
43
Categorie Soggetti
Biology,"Cell Biology","Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
Current opinion in genetics & development → ACNP
ISSN journal
0959437X
Volume
8
Issue
4
Year of publication
1998
Pages
430 - 435
Database
ISI
SICI code
0959-437X(1998)8:4<430:PALOWS>2.0.ZU;2-N
Abstract
Cellular mechanisms for the transport and localization of Wnt signalin g components are important for the propagation, distribution, and pola rization of Wnt signals in embryonic tissues. Wnt signals are distribu ted through tissues by vesicular transport of Wnt proteins, localized in embryos by directed transport of cytoplasmic Wnt-signaling componen ts, and propagated asymmetrically during cell division.