REGIOSELECTIVE AND STEREOSELECTIVE RING-OPENING OF EPOXIDES WITH AMIDE CUPRATE REAGENTS

Authors
YAMAMOTO Y ASAO N MEGURO M TSUKADA N NEMOTO H SADAYORI N WILSON JG NAKAMURA H
Citation
Y. Yamamoto et al., REGIOSELECTIVE AND STEREOSELECTIVE RING-OPENING OF EPOXIDES WITH AMIDE CUPRATE REAGENTS, Journal of the Chemical Society, Chemical Communications, (15), 1993, pp. 1201-1203
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
15
Year of publication
1993
Pages
1201 - 1203
Database
ISI
SICI code
0022-4936(1993):15<1201:RASROE>2.0.ZU;2-F
Abstract
Amide cuprate reagents attack the less hindered carbon atom of epoxide s to give 1,2-amino alcohols in good yields; this procedure is applied to the synthesis of an aziridine alcohol bearing a carborane framewor k which is a potentially useful B-10 carrier for boron neutron capture therapy.