-ACETOXYAMINO-2-TRIFLUOROMETHYLQUINAZOLIN-4(3H)ONE AS AN AZIRIDINATING AGENT FOR ALKENES

Authors
ATKINSON RS COOGAN MP CORNELL CL
Citation
Rs. Atkinson et al., -ACETOXYAMINO-2-TRIFLUOROMETHYLQUINAZOLIN-4(3H)ONE AS AN AZIRIDINATING AGENT FOR ALKENES, Journal of the Chemical Society, Chemical Communications, (15), 1993, pp. 1215-1216
Citations number
8
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
15
Year of publication
1993
Pages
1215 - 1216
Database
ISI
SICI code
0022-4936(1993):15<1215:-AAA>2.0.ZU;2-N
Abstract
The title compound 4, prepared by lead tetraacetate oxidation of 5, is stable at room temperature and aziridinates alkenes in better yield a nd higher diastereoselectivity than, e.g. the 2-ethyl compound 1; hydr azinolysis of the quinazolinone ring in 20 gives the corresponding N-a minoaziridine 21 in 64% yield.