MICROSCOPIC AND HISTOCHEMICAL EVALUATION OF DEMINERALIZED FREEZE-DRIED BONE ALLOGRAFT IN ASSOCIATION WITH IMPLANT PLACEMENT - A CASE-REPORT

A case report is presented in which a titanium implant was placed into a defect resulting from the extraction of an impacted tooth; the defe ct was filled with demineralized freeze-dried bone allograft particles without a membrane barrier. After a 6-month healing period the bone d efect had completely healed and the tissue present had macroscopic fea tures similar to mature bone. Histologic examination of this tissue sh owed that in all demineralized freeze-dried bone allograft particles, mineralization nodules were scattered inside the demineralized bone; i n the areas where the mineralization nodules were present, osteocyte l acunae could be observed. In the case presented significant new vital bone formation was observed 6 months after placement of a demineralize d freeze-dried bone allograft.