OVARIAN EPITHELIAL CARCINOMA METASTATIC TO THE CHOROID OF THE EYE - PROLONGED SURVIVAL WITH RADIATION AND TAXOL CHEMOTHERAPY

A 64-year-old was diagnosed with a stage laII clear cell adenocarcinom a of the ovary in 1986. Initial chemotherapy was with Cisplatinum, Cyt oxan, and Adriamycin. A pelvic recurrence developed in 1991 which fail ed to respond to Carboplatin therapy, and progression of disease with retroperitoneal nodal and choroidal metastases was noted in 1992. Debu lking of retroperitoneal disease along with radiotherapy and seventeen cycles of Taxol chemotherapy resulted in a sustained clinical remissi on for three years until December 1995 when a right pelvic recurrence was noted. The patient underwent resection of disease again and was re started on Taxol which was continued for six cycles until increasing s erum CA-125 and recurrent pelvic disease were noted.