E. Poreba et al., STUDY ON INTERACTION OF PROTEINS ISOLATED FROM EPITHELIAL CERVICAL TISSUE WITH GLUCOCORTICOID-RESPONSE ELEMENT OF HPV16, European journal of gynaecological oncology, 19(4), 1998, pp. 394-398
Genital HPV16 has tropism to cervical epithelial tissue which is highl
y steroid hormone dependent. Protein/DNA interaction with the fragment
of viral DNA containing the glucocorticoid-response element (GRE/PRE)
did not indicate the proteins which can bind to the GRE element in no
rmal epithelial cervical tissue. NFI is one of the cellular factors wh
ich can participate in the transcription of viral genes in study tissu
e.