R. Meisel et al., SYNTHESIS OF BRANCHED-CHAIN 2-DEOXYOCT-3-ULOSONIC ACID-DERIVATIVES ASPRECURSORS FOR C-NUCLEOSIDE ANALOGS, Journal of carbohydrate chemistry, 17(7), 1998, pp. 1057-1081
Reaction of 2,3,4,5,6-penta-O-acetyl-D-galactonic 1 and D-gluconic aci
d chloride 2, respectively, with derivatives of malonic acid furnished
substituted 2-deoxyoct-3-ulosonic acid esters, amides, and nitriles.
Further modification was carried out by O-acylation and halogenation.