Dj. Houghton et al., CHEST COMPUTERIZED-TOMOGRAPHY SCANNING IN PATIENTS PRESENTING WITH HEAD AND NECK-CANCER, Clinical otolaryngology and allied sciences, 23(4), 1998, pp. 348-350
Between 1 to 16% of patients with head and neck squamous cell carcinom
a (HNSCC) have synchronous tumours; the majority (>50%) occurring with
in the lung. Previous studies have relied upon endoscopy and chest rad
iographs. The aim of this study was to determine the incidence of sync
hronous intrapulmonary tumours in this group of patients using compute
rized tomography (CT) scanning. Over 36 months, 111 consecutive patien
ts were assessed at presentation by contrast enhanced CT scanning from
the skull base to the diaphragm. Chest scans showed intrapulmonary le
sions in 17 patients and 10 have, with time, been confirmed as neoplas
tic. These allowed treatment of three primary bronchial carcinomas fol
lowing radical treatment of the index tumour and cancellation of radic
al treatment in five patients with metastases. Two patients with possi
ble metastases at presentation underwent radical treatment to the inde
x tumour with subsequent follow-up confirming metastatic chest disease
. All 10 patients eventually died of either locoregional or metastatic
disease. This is one of the first prospective reports of chest scanni
ng in patients with head and neck cancer. An additional chest scan in
this group, many of whom undergo a staging scan of the neck, requires
an extra 10 min with no further contrast and in this study yielded a s
ynchronous tumour rate of 9%.