A reduction of 50 % or more in diabetes-related amputations is a prima
ry target of the St Vincent Declaration. This is thought to be achieva
ble because both primary and secondary preventative healthcare strateg
ies are effective in reducing the incidence of diabetic foot ulceratio
n and progression to amputation. Unfortunately there is a group who ca
nnot benefit from preventative health care, that is, newly diagnosed d
iabetic patients with already established severe complications. Using
our population-based district diabetes information system we investiga
ted, during the period 1 January 1992 to 31 December 96, the incidence
and prevalence of lower extremity amputations (LEAs) and the proporti
on occurring in patients newly or recently diagnosed as having diabete
s. Seventy-nine diabetic patients (59 male, 20 female) were recorded a
s having had 94 LEAs, the incidence of diabetes-related LEA being 475
per 100 000 diabetic patient-years. Of these LEAs 16 (20.2 %) were per
formed within 1 year of diabetes being diagnosed. This study highlight
s an appreciable and previously unrecognized problem: patients present
ing with established complications of diabetes who cannot benefit from
secondary preventative healthcare. These patients pose a potential ob
stacle to achieving targets for reductions in diabetes-related amputat
ions. (C) 1998 John Wiley & Sons, Ltd.