ANTISENSE THERAPEUTICS

Authors
Citation
S. Agrawal et Qy. Zhao, ANTISENSE THERAPEUTICS, Current opinion in chemical biology, 2(4), 1998, pp. 519-528
Citations number
52
Categorie Soggetti
Biology,Biophysics
ISSN journal
13675931
Volume
2
Issue
4
Year of publication
1998
Pages
519 - 528
Database
ISI
SICI code
1367-5931(1998)2:4<519:>2.0.ZU;2-2
Abstract
The field of antisense therapeutics has attracted great interest durin g the past decade. A large body of literature has recently appeared in which the antisense mechanism is claimed to be involved and a number of human clinical trials are underway. Questions regarding the specifi city of action and side effects of antisense phosphorothioate oligonuc leotides have arisen simultaneously.