The cleaning power of detergents seems to have peaked; all detergents
contain similar ingredients and are based on similar detergency mechan
isms. To improve detergency, modern types of heavy-duty powder detegen
ts and automatic dishwasher detergents usually contain one or more enz
ymes, such as protease. amylase, cellulase, and lipase. Alkaliphilic B
acillus strains are often good sources of alkaline extracellular enzym
es, the properties of which fulfil the essential requirements for enzy
mes to be used in detergents. We have isolated numbers of alkaliphilic
Bacillus that produce such alkaline detergent enzymes, including cell
ulase (CMCase), protease, alpha-amylase, and debranching enzymes, and
have succeeded in large-scale industrial production of some of these e
nzymes. Here, we describe the enzymatic properties, genetics, and stru
ctures of the detergent enzymes that we have developed.