USE OF VANCOMYCIN IN VITRECTOMY INFUSION SOLUTION AND EVALUATION OF RETINAL TOXICITY

Authors
BORHANI H PEYMAN GA WAFAPOOR H
Citation
H. Borhani et al., USE OF VANCOMYCIN IN VITRECTOMY INFUSION SOLUTION AND EVALUATION OF RETINAL TOXICITY, International ophtalmology, 17(2), 1993, pp. 85-88
Citations number
15
Categorie Soggetti
Ophthalmology
Journal title
International ophtalmology → ACNP
ISSN journal
01655701
Volume
17
Issue
2
Year of publication
1993
Pages
85 - 88
Database
ISI
SICI code
0165-5701(1993)17:2<85:UOVIVI>2.0.ZU;2-9
Abstract
The retinal toxicity of vancomycin in infusion solution used in vitrec tomy and lensectomy was investigated in rabbit eyes by means of electr oretinography and histologic study (light microscopy). Concentrations of 8 mug/ml, 16 mug/ml, and 32 mug/ml of vancomycin in balanced salt s olution caused no abnormal ERG or histologic changes. However, ERG amp litude depression and abnormal histologic changes occurred when the co ncentration of 100 mug/ml of vancomycin was used.