EXPRESSION OF THE MOUSE REN-2 GENE IN THE SMALL-INTESTINE IS REGULATED BY FOOD-INTAKE

Citation
Z. Yi et al., EXPRESSION OF THE MOUSE REN-2 GENE IN THE SMALL-INTESTINE IS REGULATED BY FOOD-INTAKE, Pflugers Archiv, 424(3-4), 1993, pp. 199-202
Citations number
39
Categorie Soggetti
Physiology
Journal title
ISSN journal
00316768
Volume
424
Issue
3-4
Year of publication
1993
Pages
199 - 202
Database
ISI
SICI code
0031-6768(1993)424:3-4<199:EOTMRG>2.0.ZU;2-H
Abstract
The existence of a local renin/angiotensin system in the intestine of mammals is speculative despite the known importance of angiotensin II for water and electrolyte homeostasis. We demonstrate the presence of ren-2 transcripts in the small intestine of DBA/2 mice. The marked exp ression of the ren-2 gene is blunted tissue-specifically by starvation , corroborating a local renin/angiotensin system in this organ.