Vocal cord dysfunction (VCD) is a respiratory disorder often confused
with asthma. Although previous case reports have implicated family and
/or individual psychopathology in the etiology of this condition, this
is the first paper to present prospective, case-control empirical dat
a on a group of pediatric patients with VCD. A case-control methodolog
y was employed to examine patients in terms of both family and individ
ual functioning. Results indicate that patients with VCD were not diff
erent from asthmatic controls on measures of family functioning. Howev
er, they did experience significantly higher levels of anxiety and rec
eived a higher number of anxiety-related diagnoses such as separation
anxiety and generalized anxiety disorder on a structured psychiatric i
nterview. The nature of the relation between VCD and psychological sym
ptoms in children is discussed. Etiologic and treatment issues are exa
mined in the context of the findings.