RIBOZYME - RNA AS AN ENZYME, BUT AS A THERAPEUTIC

Citation
Jf. Burke et Sm. Thomas, RIBOZYME - RNA AS AN ENZYME, BUT AS A THERAPEUTIC, Expert opinion on therapeutic patents, 8(9), 1998, pp. 1093-1097
Citations number
2
Categorie Soggetti
Medicine, Legal","Pharmacology & Pharmacy
ISSN journal
13543776
Volume
8
Issue
9
Year of publication
1998
Pages
1093 - 1097
Database
ISI
SICI code
1354-3776(1998)8:9<1093:R-RAAE>2.0.ZU;2-9
Abstract
Ribozyme Pharmaceuticals, Inc. is based on a distinctive technology wh ich uses antisense molecules that are also enzymes. An obvious use of these molecules is in the cleavage of mRNA for genes expressed in dise ase states portfolio of patented ribozyme sequences relevant to a wide range of or those encoded by infecting viruses. The Company has an im pressive disorders, although questions remain over the degree of homol ogy needed to target the enzyme and their stability and activity.