DIFFERENTIAL EXPRESSION OF THE ZINC-FINGER GENE ZFP105 DURING SPERMATOGENESIS

Authors
PRZYBORSKI SA KNOWLES BB HANDEL MA GURWITCH SA ACKERMAN SL
Citation
Sa. Przyborski et al., DIFFERENTIAL EXPRESSION OF THE ZINC-FINGER GENE ZFP105 DURING SPERMATOGENESIS, Mammalian genome, 9(9), 1998, pp. 758-762
Citations number
38
Categorie Soggetti
Biology,"Genetics & Heredity","Biothechnology & Applied Migrobiology
Journal title
Mammalian genome → ACNP
ISSN journal
09388990
Volume
9
Issue
9
Year of publication
1998
Pages
758 - 762
Database
ISI
SICI code
0938-8990(1998)9:9<758:DEOTZG>2.0.ZU;2-N
Abstract
We report the isolation of Zfp105, the mouse homolog of the human ZNF3 5 zinc finger gene. Zfp105 and ZNF35 are highly conserved at the prote in and nucleotide level, and Zfp105 maps to a region of mouse Chromoso me (Chr) 9 that is homologous to the human region containing ZNF35. Zp f105 is highly expressed in the testis, especially in pachytene sperma tocytes and round spermatids. The possible role of this gene product i n maintaining an ordered germ cell differentiation process is discusse d.