COLONIC PSEUDOOBSTRUCTION DUE TO BETA-2-MICROGLOBULIN AMYLOIDOSIS AFTER LONG-TERM HEMODIALYSIS

beta 2-Microglobulin (A beta(2)M) amyloidosis is a relatively new seco ndary amyloidosis associated with renal failure and haemo- and periton eal dialysis. Although beta 2-microglobulin depositions are systemic, clinical manifestations are limited to articular and para-articular di sease in most cases. A very limited number of patients have been repor ted with extra-articular manifestations including those of the gastroi ntestinal tract. We report on a patient who was treated with haemodial ysis for 23 years and developed colonic pseudo-obstruction due to A be ta(2)M amyloidosis. (C) 1998 Lippincott Williams & Wilkins.