CONFORMATIONAL STUDIES OF NATURAL-PRODUCTS .4. CONFORMATION AND ABSOLUTE-CONFIGURATION OF CASCAROSIDE-A, CASCAROSIDE-B, CASCAROSIDE-C, CASCAROSIDE-D

Authors
MANITTO P MONTI D SPERANZA G MULINACCI N VINCIERI FF GRIFFINI A PIFFERI G
Citation
P. Manitto et al., CONFORMATIONAL STUDIES OF NATURAL-PRODUCTS .4. CONFORMATION AND ABSOLUTE-CONFIGURATION OF CASCAROSIDE-A, CASCAROSIDE-B, CASCAROSIDE-C, CASCAROSIDE-D, Journal of the Chemical Society. Perkin transactions. I, (14), 1993, pp. 1577-1580
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
14
Year of publication
1993
Pages
1577 - 1580
Database
ISI
SICI code
0300-922X(1993):14<1577:CSON.C>2.0.ZU;2-0
Abstract
H-1 and C-13 NMR spectra for the four carthartic constituents of Casca ra bark, namely, the cascarosides A-D are recorded. The conformation a nd absolute configuration of each component of the two diastereoisomer ic pairs have been determined on the basis of anisotropic effects and specific NOE (nuclear Overhauser effects) in their H-1 NMR spectra. CD spectra for these anthrone C,O-diglucosides are reported.