A NEW AND SIMPLE LEGO SYSTEM FOR THE SYNTHESIS OF BRANCHED OLIGOPYRIDINES

Authors
PABST GR SCHMID K SAUER J
Citation
Gr. Pabst et al., A NEW AND SIMPLE LEGO SYSTEM FOR THE SYNTHESIS OF BRANCHED OLIGOPYRIDINES, Tetrahedron letters, 39(37), 1998, pp. 6691-6694
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
37
Year of publication
1998
Pages
6691 - 6694
Database
ISI
SICI code
0040-4039(1998)39:37<6691:ANASLS>2.0.ZU;2-3
Abstract
The condensation of carboxamidrazones 1 with 1,2-dicarbonyl compounds 2 is the best method for the synthesis of alkyl, aryl or hetaryl subst ituted 1,2,4-triazines 3 - 7. These 1,2,4-triazines can be easily tran sformed to pyridines 8 - 12 by [4+2] cycloaddition with bicyclo[2.2.1] hepta-2,5-diene followed by [4+2] cycloreversions of nitrogen and cycl opentadiene. This reaction sequence offers a new, simple and general a ccess to branched oligopyridines. (C) 1998 Elsevier Science Ltd. All r ights reserved.