ENANTIOCONSERVATIVE SYNTHESIS AND RING CLOSING METATHESIS OF DISUBSTITUTED DIALKENIC AMIDES

Authors
SAURIATDORIZON H GUIBE F
Citation
H. Sauriatdorizon et F. Guibe, ENANTIOCONSERVATIVE SYNTHESIS AND RING CLOSING METATHESIS OF DISUBSTITUTED DIALKENIC AMIDES, Tetrahedron letters, 39(37), 1998, pp. 6711-6714
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
37
Year of publication
1998
Pages
6711 - 6714
Database
ISI
SICI code
0040-4039(1998)39:37<6711:ESARCM>2.0.ZU;2-0
Abstract
Optically pure disubstituted dialkenic amides 2, which are direct prec ursors of Z-ethylenic pseudopeptides 1, are readily synthesized and th en cyclized to lactams 3 in the presence of Grubbs' ruthenium-based me tathesis catalysts with total conservation of enantiomeric purity. (C) 1998 Elsevier Science Lid. All rights reserved.