LEWIS-ACID MEDIATED RING-OPENING OF PROPARGYLIC EPOXIDES - A STEREOSPECIFIC SYNTHESIS OF 1,2-DISUBSTITUTED HOMOPROPARGYLIC ALCOHOLS

Authors
BERNARD N CHEMLA F NORMANT JF
Citation
N. Bernard et al., LEWIS-ACID MEDIATED RING-OPENING OF PROPARGYLIC EPOXIDES - A STEREOSPECIFIC SYNTHESIS OF 1,2-DISUBSTITUTED HOMOPROPARGYLIC ALCOHOLS, Tetrahedron letters, 39(37), 1998, pp. 6715-6718
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
37
Year of publication
1998
Pages
6715 - 6718
Database
ISI
SICI code
0040-4039(1998)39:37<6715:LMROPE>2.0.ZU;2-A
Abstract
Thr BF3-Et2O-mediated ring opening of propargylic epoxides by organome tallic nucleophiles gives in a completely regio- and stereospecific fa shion 1,2-disubstituted homopropargylic alcohols in good to excellent yields. (C) 1998 Elsevier Science Lid. All rights reserved.