ULTRASOUND PRENATAL-DIAGNOSIS OF THE NAIL-PATELLA SYNDROME

The Nail-Patella syndrome (NPS) is an autosomal dominant connective-ti ssue disorder characterized by the absence or hypoplasia of the nails and patella, posterior illiac horns, elbow deformities, congenital nep hropathy cervical ribs and eye problems. The presence of the posterior iliac horns is pathognomonic and have been observed in more than 80 p er cent of cases. In this report, we present the first case of prenata l diagnosis of NPS by ultrasound. The possible kidney involvement, com bined with other, milder. complications make the prenatal diagnosis of this syndrome worthwhile. (C) 1998 John Wiley & Sons, Ltd.