NOVEL POTENTIAL ENANTIOSELECTIVE PHASE-TRANSFER CATALYSTS BASED ON LUPININE

Authors
DEHMLOW EV KLAUCK R NEUMANN B STAMMLER HG
Citation
Ev. Dehmlow et al., NOVEL POTENTIAL ENANTIOSELECTIVE PHASE-TRANSFER CATALYSTS BASED ON LUPININE, Journal fur praktische Chemie, Chemiker-Zeitung, 340(6), 1998, pp. 572-575
Citations number
16
Categorie Soggetti
Chemistry,"Chemistry Applied
Journal title
Journal fur praktische Chemie, Chemiker-Zeitung → ACNP
ISSN journal
09411216
Volume
340
Issue
6
Year of publication
1998
Pages
572 - 575
Database
ISI
SICI code
0941-1216(1998)340:6<572:NPEPCB>2.0.ZU;2-O
Abstract
Ten N-alkylated lupininium derivatives 5-8 were prepared as potential enantioselective phase transfer catalysts. Compounds 5a-d, 6a-d contai n four asymmetric centers (including one in the side chain) with known configuration resting on an X-ray structure. Preliminary PT catalytic experiments in several reactions gave high chemical yields but relati vely disappointing enantioselectivities.