STARFISH SAPONINS .50. STEROIDAL GLYCOSIDES FROM THE OKINAWAN STARFISH NARDOA-TUBERCULATA

This paper describes a complete analysis of the glycoside and polyhydr oxysteroid constituents of the starfish Nardoa tuberculata, collected at Zampa, Okinawa, Japan. Besides a group of known non-sulfated steroi dal diglycosides, halitylosides A 5!, B 6!, D 7!, E 8!, and F 9!, and two known polyhydroxysteroids 10 and 11, N. tuberculata also cont ains four new sulfated steroidal glycosides 1-4 closely related to the previous halitylosides. The antifungal activities and the effects on the development of fertilized sea urchin eggs of some steroid componen ts from this starfish were examined.