MANAGEMENT OF RADIATION FAILURE FOR LOCALIZED PROSTATE-CANCER

Due to the historically large number of patients with localized prosta te cancer (CAP) treated by radiation therapy, an increasing number of patients are presenting local failure. The currently available concept s regarding its definition as well as management options are reviewed. The literature regarding radiation failure for localized prostate can cer was reviewed. Emphasis was made on articles concerning definition of radiation failure, patient evaluation and restaging and definitive as well as palliative management options. There is definitely a subset of patients with locally recurrent prostate cancer without evidence o f metastasis that could potentially benefit from aggressive local ther apy A treatment algorithm is proposed but it should be emphasized that treatment options should be individualized to suit the need of a part icular patient.