OSTIAL RENAL-ARTERY STENT PLACEMENT FOR ATHEROSCLEROTIC RENAL-ARTERY STENOSIS IN PATIENTS WITH CORONARY-ARTERY DISEASE

To test the utility of endoprosthetic treatment for ostial renal arter y stenosis, and to examine blood pressure and its treatment, serum cre atinine, and restenosis rate, 44 ostial renal stent placements were pe rformed in 30 patients with concomitant coronary artery disease, arter ial hypertension, and the indication for angiotensin converting enzyme (ACE) therapy, There was a marked decrease in systolic and diastolic blood pressure (163 +/- 30 to 145 +/- 17 and 93 +/- 18 to 83 +/- 10 mm Hg; P < 0.008) with a decrease in number of medication (3.2 +/- 0.9 t o 2.8 +/- 1.0; P = 0,005), In 5 out of 8 patients not receiving an ACE inhibitor, this drug could be added, Serum creatinine changed from 1. 46 +/- 0.7 mg/dl to 1.39 +/- 0.58 mg/dl (P = ns). Three patients showe d restenosis (12.5%), Ostial stenting lowers blood pressure, decreases antihypertensive drugs and increases medication flexibility. (C) 1998 Wiley-Liss, Inc.