Testing embryonic cells for genetic abnormalities gives us the capacit
y to predict whether and to what extent people will exist with disease
and disability. Moreover, the freezing of embryos for long periods of
time enables us to alter the length of a normal human lifespan. After
highlighting the shortcomings of somatic-cell gene therapy and perm-l
ine genetic alteration, I argue that the testing and selective termina
tion of genetically defective embryos is the only medically and morall
y defensible may to prevent the existence of people with severe disabi
lity, pain and suffering that make their lives not worth living for th
em on the whole. In addition, I consider the possible harmful effects
on children born from frozen embryos after the deaths of their biologi
cal parents, or when their parents are at an advanced age. I also expl
ore whether embryos have moral status and whether the prospects for di
sease-preventing genetic alteration can justify long-term cryopreserva
tion of embryos.