Cg. Armstrong et al., CLONING OF A NOVEL TESTIS-SPECIFIC PROTEIN SERINE THREONINE PHOSPHATASE, PPN 58A, FROM DROSOPHILA-MELANOGASTER/, Biochimica et biophysica acta, N. Gene structure and expression, 1399(2-3), 1998, pp. 234-238
A gene encoding a novel member of the PPP family of protein serine/thr
eonine phosphatases, termed PPN 58A, was cloned from Drosophila melano
gaster. The deduced amino acid sequence of PPN 58A exhibits 59-62% ide
ntity to D, melanogaster PP1 isoforms, 51% identity to D. melanogaster
PPY 55A and less than or equal to 40% identity to other members of th
e PPP family. The single copy gene PPN 58A maps to chromosome 2 locus
58A. Analysis of PPN 58A mRNA reveals that, like PPY 55A, PPN 58A is a
testis specific enzyme. (C) 1998 Elsevier Science B.V. All rights res
erved.