IDENTIFICATION OF N-2-(1-CARBOXYMETHYL)GUANINE (CMG) AS A GUANINE ADVANCED GLYCATION END-PRODUCT

Authors
ALABED Y SCHLEICHER E VOELTER W LIEBICH H PAPOULIS A BUCALA R
Citation
Y. Alabed et al., IDENTIFICATION OF N-2-(1-CARBOXYMETHYL)GUANINE (CMG) AS A GUANINE ADVANCED GLYCATION END-PRODUCT, Bioorganic & medicinal chemistry letters, 8(16), 1998, pp. 2109-2110
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
16
Year of publication
1998
Pages
2109 - 2110
Database
ISI
SICI code
0960-894X(1998)8:16<2109:ION(AA>2.0.ZU;2-U
Abstract
The reaction of D-glucose with 9-methylguanine produces N-2-fructosyl- 9-methylguanine, which undergoes oxidation to produce N-2-(1-carboxyme thyl)-9-methylguanine as a major adduct. (C) 1998 Elsevier Science Ltd . All rights reserved.